Due to an experimental vaccine, Dr. Robert Neville is the only human survivor of an apocalyptic war waged with biological weapons. Besides him, only a few hundred deformed, nocturnal people remain - sensitive to light, and homicidally psychotic.
In 1953, an innocent man named Christopher Emmanuel "Manny" Balestrero is arrested after being mistaken for an armed robber.
A man convicted of murdering his wife escapes from prison and works with a woman to try and prove his innocence.
