The Macahans, a family from Virginia headed by Zeb Macahan, travel across the country to pioneer a new land and a new home in the American West.
The Cavalcade of Perversion, a traveling freak show, acts as a front for Divine, who is out for blood after discovering her lover's affair.
A psychopath escapes from a mental institution and starts a murder spree, which ends in the pursuing of a young handicapped girl, who once got a blood transfusion from him.
