The Three Mesquiteers convince a group of settlers to exchange their present property for some which, unbeknownst to our goodguys, is going to be worthless. They are captured before they can warn the ranchers.
Rancher Tim Clark borrows money from Bob Russell, who then rustles Clark's cattle so he will be unable to repay the money. Thus Russell is able to cheat Clark out of his ranch. Clark becomes a prospector for silver and ultimately comes to settle accounts with Russell and crooked deputy Bendix.
After gold shipments from a mining town have been hijacked, the three Mesquiteers buy a plane to fly the gold out. The owner of the shipping line brings in Eastern gangsters to thwart them.