Bruno Fioretti, known as "Mandrake", is an inveterate gambler who never misses a day at the horse racing track in Rome. He is doubly unlucky: he bets too much on one horse, and his wife is sleeping with his best friend because Mandrake is always at the track. Penniless and cuckolded, Mandrake decides to make one last bet.
Boston, 1920. Italian immigrants Nicola Sacco and Bartolomeo Vanzetti are charged and unfairly tried for murder on the basis of their anarchist political beliefs.
Expert conman Joe Thanks teams up with half-breed Bill and naive Lucy to steal $300,000 from the Indian-hating Major Cabot. Their elaborate plan is full of disguises, double-crosses, and chases, but Joe always seems to know what he's doing.
