Arjun is a theater artist who is suffering from an illness and has to take a pill every 56 minutes. Parallel to his misery is a murder investigation of three neurosurgeons lead by CBI officer Priya Krishna. Priya meets Dr Ashwath and the two go on an exposition about the medical mafia and its consequences.
In the early 1970s, a petty criminal Kaali unwittingly involves himself with underworld thugs, catalyzing events beyond his control.