Twenty-eight-year-old Margot is happily married to Lou, a good-natured cookbook author. But when Margot meets Daniel, a handsome artist who lives across the street, their mutual attraction is undeniable.
Straitlaced Princeton University admissions officer Portia Nathan is caught off-guard when she makes a recruiting visit to an alternative high school overseen by her former classmate, the freewheeling John Pressman. Pressman has surmised that Jeremiah, his gifted yet very unconventional student, might well be the son that Portia secretly gave up for adoption many years ago.
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Isaac begins the process of gender re-assignment while his younger brother Logan must deal with a new sister and the grief of losing his older brother.
