Vetri (Ajmal), Professor (Mano) and Ganesh run away from Chennai to Ooty, where they meet a lawyer Sujatha (Radhika Apte). For Sujatha it is love at first sight as she falls for Vetri. Sujatha discovers after an accident that police are on their trail and they are accused in a murder case after escaping from a mental health institute.
The story features the friendship between a father and son. Maanikunju was living his dream when the 17-years-old Vishnu walks in to their life. With some hidden intentions, Vishnu befriends Maanikunju and his friends. But the nature of his father leaves him surprised. Another person Shankaran Nampoothirippad acts as a tool between the two. What follows next forms the rest of the story.
Flat No.4B is a family oriented Malayalam movie based on social commitment element directed by Krishnajith S Vijayan and produced by Arun Prasad.
