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Se-ha who is a physically handicapped and Dong-gu who is a mentally handicapped are not their own brothers. But while living 20 years together, the two became indispensable to each other. One day, the mother of Dong-gu suddenly visits him and acts as his guardian.
Whenever elementary school teacher Kang Joon-soo falls in love, he always gives too much of himself to the relationship. Yet despite that, he ends up being the one getting dumped by his girlfriends. Joon-soo has been friends for 18 years with Kim Hyun-woo, a weather forecaster whose beauty belies her witty tongue and aggressive manner.
An old bachelor Seok-joong, who has no experience in dating, falls in love at first sight with a prostitute named Eun-ha. At first Eun-ha shows no interest in Seok-joong, but gradually she begins to be flattered by his devotion and eventually falls in love with him. They marry. However, one day, Eun-ha finds out that she is infected with HIV and decides to leave Seok-joong.
