Loosely based on the true-life tale of Ron Woodroof, a drug-taking, women-loving, homophobic man who in 1986 was diagnosed with HIV/AIDS and given thirty days to live.
While attending a party at James Franco's house, Seth Rogen, Jay Baruchel and many other celebrities are faced with the apocalypse.
An extremely wealthy elderly man dying from cancer undergoes a radical medical procedure that transfers his consciousness to the body of a healthy young man but everything may not be as good as it seems when he starts to uncover the mystery of the body's origins and the secret organization that will kill to keep its secrets.