A wealthy New Orleans businessman becomes obsessed with a young woman who resembles his late wife.
Warren Maxwell, the owner of a run-down plantation, pressures his son, Hammond, to marry and produce an heir to inherit the plantation. Hammond settles on his own cousin, Blanche, but purchases a sex slave when he returns from the honeymoon. He also buys his father a new Mandingo slave named Mede to breed and train as a prize-fighter.
A medical examiner discovers that an innocent shooting victim in a robbery died of bubonic plague. With only 48 hours to find the killer, who is now a ticking time bomb threatening the entire city, a grisly manhunt through the seamy underworld of the New Orleans Waterfront is underway.
