After Port Royal is attacked and pillaged by a mysterious pirate crew, capturing the governor's daughter Elizabeth Swann in the process, William Turner asks free-willing pirate Jack Sparrow to help him locate the crew's ship—The Black Pearl—so that he can rescue the woman he loves.
Young teenager Sam Witwicky becomes involved in the ancient struggle between two extraterrestrial factions of transforming robots – the heroic Autobots and the evil Decepticons. Sam holds the clue to unimaginable power and the Decepticons will stop at nothing to retrieve it.
Dr. Gregory House, a drug-addicted, unconventional, misanthropic medical genius, leads a team of diagnosticians at the fictional Princeton–Plainsboro Teaching Hospital in New Jersey.