Izo is an assassin in the service of a Tosa lord and Imperial supporter. After killing dozens of the Shogun's men, Izo is captured and crucified. Instead of being extinguished, his rage propels him through the space-time continuum to present-day Tokyo. Here Izo transforms himself into a new, improved killing machine.
A barkeeper saves a Yakuza boss' life and thus makes his way up in the organization. However, his fear of nothing soon causes problems.
When a young Yakuza torments the customers in a rival crime family's nightclub, it is not long before his dead body is found. Soon, inter-family retaliation follows, resulting in the death for a prominent crime boss. Devastated by this turn of events, the temperamental Kenzaki vows to avenge his boss's death and, as bloody violence ensues, the body count reaches excessive proportions.
