Will Turner and Elizabeth Swann join forces with the revived Captain Barbossa to free Jack Sparrow from Davy Jones' locker. The group must navigate dangerous waters, confront many foes and, ultimately, choose sides in a battle wherein piracy itself hangs in the balance.
When a mysterious woman seduces Dom into the world of crime and a betrayal of those closest to him, the crew face trials that will test them as never before.
Dr. Gregory House, a drug-addicted, unconventional, misanthropic medical genius, leads a team of diagnosticians at the fictional Princeton–Plainsboro Teaching Hospital in New Jersey.