The chilling and relentless Jigsaw killer returns to terrorize the city once again. When a gruesome murder victim emerges with unmistakable traces of Jigsaw's sinister methods, Detective Eric Matthews is thrust into a high-stakes investigation. To his surprise, apprehending Jigsaw seems almost too easy, but what he doesn't realize is that being caught is merely another piece of Jigsaw's intricate puzzle.
The film tells the story of two good friends who live together, Andrew, an agoraphobic travel agent who works from his home, and Dave, a loser who works in an office where he is treated with contempt. Just when it seems things can't get any worse for the two, the entire world outside of their house disappears and is replaced with an endless white void.
Fifteen years after a murderer is convicted he is released and all the witnesses against him begin to be murdered.
