The government sets up a zombie squad after an epidemic has made the world run rampant with living corpses. The team head off to Ohio to try and find a cure but soon run into a crazy cult of zombie lovers who are set on preserving the walking dead as they believe it's God's will.
During a drug raid, a narcotics officer confronts a strange Voodoo priest named Dr. Death, who is chanting. The officer and the priest shoot it out and they both wind up dead. Later, the two rise from their graves and return to the land of the living as zombies. Dr. Death is resurrected with a new mission in mind, to take over the world. The "zombie" cop enlists the aid of his old police buddies to stop the mad priest.
While on a stakeout, hardboiled cop Eddie Boone gets injected with a dangerous new designer drug causing nightmarish side effects. As he searches for his missing partner, Eddie discovers the urban streets full of mutants, monsters, and mayhem orchestrated by the mastermind behind the lethal narcotic.
