The supernatural grudge manifests itself by way of a strange cyst growing in the body of a young woman, slowly draining all life from her in revenge for... what?
Released to commemorate Kamen Rider 555's 20th anniversary, the film takes place after the ending of the TV series. Masato Kusaka and Mari Sonoda are fighting a new iteration of Smart Brain led by Kitazaki, who begins an operation to exterminate all Orphnochs, with Takumi Inui seemingly working with them for unknown reasons since his disappearance.
Takumi, Mari, Masato, and many other people who work at Kikuchi Cleaning Shop are leading their daily lives as usual. One day, a customer visiting the store is suddenly killed by someone, they need to try to find out who the murderer is...
