Peter Parker is going through a major identity crisis. Burned out from being Spider-Man, he decides to shelve his superhero alter ego, which leaves the city suffering in the wake of carnage left by the evil Doc Ock. In the meantime, Parker still can't act on his feelings for Mary Jane Watson, a girl he's loved since childhood. A certain anger begins to brew in his best friend Harry Osborn as well...
Dr. Gregory House, a drug-addicted, unconventional, misanthropic medical genius, leads a team of diagnosticians at the fictional Princeton–Plainsboro Teaching Hospital in New Jersey.
Ed Deline is a strict ex-CIA officer who went from being Head of Security to becoming President of Operations of the Montecito, whose job is to run the day-to-day operations of the casino. Following his departure, former Marine Danny McCoy, Ed's former protégé, becomes the Montecito's new President of Operations.
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On the verge of completing her final mission, a hard as nails commando finds herself losing team members to an unstoppable demon of other dimensional origins and must destroy it before it escapes the facility into our world.
