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A husband-and-wife pair of retired cult deprogrammers experience marital strife when their past catches up with them.
Frictions develop when Yisroel "Izzy" Jonigkeyt, a Chassidic Jew from Crown Heights, travels to San Francisco to visit Polish-born Catholic friend Marek Wisniewski with the intent of discovering why a Bay Area art-world iconoclast named Harry Kierk seeks to destroy a lifetime's worth of his own work. As the visit progresses, Izzy and Marek discover for the first time that complex historical baggage impinges on their curious friendship and, soon, they begin to understand why Kierk is driven towards destruction. Continued encounters with Marek's vaguely anti-Semitic cousin Irek (who is their only gateway to contact Kierk) only compound these tensions.
Eddie Huntly, an east coast radio personality, moves to San Francisco to marry Thea, the sister of his best friend Neil, a successful entrepreneur. Shortly before Eddie's arrival, Neil is found murdered in what the police surmise was a simple mugging gone awry. As the sullen Eddie steps in as interim host of his old friend Dean's late-night talk-radio show, he obsessively makes regular visits to the forested spot where Neil's corpse was found. One such visit unleashes a chain of unpredictable events that sends Eddie snooping into the life of a sleepwalking drifter with a mysterious past.
Jerry, an ambulance-chasing lawyer (and 8mm film hobbyist), lapses into a deep depression after he is scammed out of his retirement savings. His intense love of W.C. Fields, of whom he does impersonations, and his commitment to both his mixed-up half-sister Karen (who is going deaf and learning sign language) is the only thing keeping him from suicide.
