Jamie is a boorish, insensitive American twentysomething traveling in Chile, who somehow manages to create chaos at every turn. He and his friends are planning on taking a road trip north to experience a legendary shamanistic hallucinogen called the San Pedro cactus. In a fit of drunkenness at a wild party, Jamie invites an eccentric woman—a radical spirit named Crystal Fairy—to come along.
Gaspar is a young, lonely cinematographer. Unable to deal with his sister and sick grandfather he spends his time with Susana, an actress working on a opera. When he meets Alvaro, an idealistic traveler, Gaspar's life changes. They embark on a adventure that help them unearth the fragility and value of human existence
