Boston pharmacist Tom Craig comes to Sacramento, where he runs afoul of local political boss Britt Dawson, who exacts protection payment from the citizenry. Dawson frames Craig with poisoned medicine, but Craig redeems himself during a Gold Rush epidemic.
Dr. Ralph Snyder and Dr. Frank Blake open an office together but soon split over a rivalry for nightclub singer Diana Wayne and a difference over ethics.
Aided by musicians at the Grand Ole Opry, a small-town mayor in the Ozarks takes on a group of crooked politicians.
