At the opening party of a colossal—but poorly constructed—skyscraper, a massive fire breaks out, threatening to destroy the tower and everyone in it.
After her younger sister gets involved in drugs and is severely injured by contaminated heroin, a nurse sets out on a mission of vengeance and vigilante justice, killing drug dealers, pimps, and mobsters who cross her path.
A group of ruthless Chicago mob enforcers are sent to Kansas City to settle things with the owner of a slaughterhouse who has taken money that is not his to keep.