Steve McGarrett returns home to Oahu, in order to find his father's killer. The governor offers him the chance to run his own task force (Five-0). Steve's team is joined by Chin Ho Kelly, Danny "Danno" Williams, and Kono Kalakaua.
Lahela 'Doogie' Kamealoha, a 16-year-old prodigy juggles a budding medical career and life as a teenager. With the support of her caring and comical 'ohana (family) and friends, Lahela is determined to make the most of her teenage years and forge her own path.
As an outbreak of leprosy engulfs 19th-century colonial Hawai'i, a small group of infected Native Hawaiians resist government-mandated exile, taking a courageous stand against the provisional government. Inspired by real-life events.