A couple with a newborn baby face unexpected difficulties after they are forced to live next to a fraternity house.
While attending a party at James Franco's house, Seth Rogen, Jay Baruchel and many other celebrities are faced with the apocalypse.
Mia, a drug addict, is determined to kick the habit. To that end, she asks her brother, David, his girlfriend, Natalie and their friends Olivia and Eric to accompany her to their family's remote forest cabin to help her through withdrawal. Eric finds a mysterious Book of the Dead at the cabin and reads aloud from it, awakening an ancient demon. All hell breaks loose when the malevolent entity possesses Mia.
