A businessman, on his daily commute home, gets unwittingly caught up in a criminal conspiracy that threatens not only his life but the lives of those around him.
A listless Wade Wilson toils away in civilian life with his days as the morally flexible mercenary, Deadpool, behind him. But when his homeworld faces an existential threat, Wade must reluctantly suit-up again with an even more reluctant Wolverine.
A group of top female agents from American, British, Chinese, Colombian, and German government agencies are drawn together to try and stop an organization from acquiring a deadly weapon to send the world into chaos.