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Sophie, a young milliner, is turned into an elderly woman by a witch who enters her shop and curses her. She encounters a wizard named Howl and gets caught up in his resistance to fighting for the king.
Young Haru rescues a cat from being run over, but soon learns it's no ordinary feline; it happens to be the Prince of the Cats.
When social worker Rika is sent to check on a traumatized old lady whose family have moved in at the site of the notorious Saeki family murder case, she unwittingly unleashes a cycle of terror that is transmitted via its victims further and further from its original source.