Guido Anselmi, a film director, finds himself creatively barren at the peak of his career. Urged by his doctors to rest, Anselmi heads for a luxurious resort, but a sorry group gathers—his producer, staff, actors, wife, mistress, and relatives—each one begging him to get on with the show. In retreat from their dependency, he fantasizes about past women and dreams of his childhood.
An English pianist living in Rome witnesses the brutal murder of his psychic neighbor. With the help of a tenacious young reporter, he tries to discover the killer using very unconventional methods. The two are soon drawn into a shocking web of dementia and violence.
Middle-aged Giulietta grows suspicious of her husband, Giorgio, when his behavior grows increasingly questionable. One night when Giorgio initiates a seance amongst his friends, Giulietta gets in touch with spirits and learns more about herself and her painful past. Slightly skeptical, but intrigued, she visits a mystic who gives her more information -- and nudges her toward the realization that her husband is indeed a philanderer.
