Having both lost their jobs, two strangers become unlikely friends after a run in with a would be robber, who is actually a hitman with a grudge against the two.
Mike Vecchio and Susan Henderson are preparing for their upcoming wedding. However, they seem to be the only two people at the wedding that are happy. Mike's brother Richie and his wife Joan are going through a divorce, which is upsetting his overly devout Catholic mother Beatrice. Also, Susan's father is carrying on an affair and her sex starved older sister Wilma is going through her troubles with her husband Johnny. All this is going on while Mike's best friend Jerry is trying to bed the maid of honor, Susan's cousin Brenda.
Elwood P. Dowd's constant companion is Harvey, a six-foot tall invisible rabbit. To his sister, his obsession with Harvey has been a thorn in her plans to marry off her daughter. However, when she decides to put Elwood in a mental institution, a mix-up occurs, and she finds herself committed instead. It's now up to Elwood and "Harvey" to straighten out the mess.
