A scientist, Dr Hollander, takes his niece Miranda to Mexico in an attempt to reverse the effects of the alien DNA he used to create her. However the treatment goes horribly wrong, and sets Miranda on a killing spree as she sets out to find a mate.
Three college students, Phil, Ed, and Henry take a road trip into Mexico for a week of drinking and carefree fun only to have Phil find himself a captive of a group of satanic Mexican drug smugglers who kill tourists and whom are looking for a group of new ones to prepare for a sacrifice.
She's sexy, shameless and loves taking people to their limit. She's a dangerous young woman who dreams about a jaguar that licks her naked body and sleeps by her side. Her past is bathed in blood and weird passions. Now she's met the man of her wildest dreams. He's dark, tough and mysterious. He likes robbing banks, trafficking in corpses and spicing it all with voodoo rituals. Together, the duo sets off toward Mexico destined to become the most feared outlaws in the continent.
