Two former high school friends Patty and Cocoy find each other unexpectedly 30 years later, not only as organizers of their high school reunion, but also as new neighbors. Patty and her daughter Yanni's quiet lives then get an unexpected shake-up when love—in the form of Cocoy and his nephew Jason —comes knocking on their door.
Winona, a sassy and spunky girl is just diagnosed with lupus, Bong, a guy who secretly loves her, will do everything for her to live to the fullest before she expires.
The film follows the life of Miggy and Laida after their break-up which occurred after the events in the second film. Miggy, is now in a relationship with Belle while Laida is now a fiercer woman after living in the United States. They try to co-exist in the same company while Laida tries to oppose Miggy's business decisions through a series of events which made them realize the real definition of true love.