Aging King George III of England is exhibiting signs of madness, a problem little understood in 1788. As the monarch alternates between bouts of confusion and near-violent outbursts of temper, his hapless doctors attempt the ineffectual cures of the day. Meanwhile, Queen Charlotte and Prime Minister William Pitt the Younger attempt to prevent the king's political enemies, led by the Prince of Wales, from usurping the throne.
Ruth Ellis lives with her ten-year old son Andy next to a night club. One night she meets David Blakely, and they start a love affair. However, for David with his upper-class background, it is impossible to uphold the relationship. He breaks up with her, something which makes Ellis, obsessed by him, very upset.
