After kidnapping a father and his two kids, the Gecko brothers head south to a seedy Mexican bar to hide out in safety, unaware of its notorious vampire clientele.
Two doctors find their graveyard shift inundated with townspeople ravaged by sores. Among the wounded is Cherry Darling, a dancer whose leg was ripped from her body. As the invalids quickly become enraged aggressors, Cherry and her ex-boyfriend El Wray lead a team of accidental warriors into the night.
El Mariachi plunges headfirst into the dark border underworld when he follows a trail of blood to the last of the infamous Mexican drug lords, Bucho, for an action-packed, bullet-riddled showdown. With the help of his friend and a beautiful bookstore owner, El Mariachi tracks Bucho, takes on his army of desperados, and leaves his own trail of blood.
