When Charlie's old friend from Scotland Yard is murdered when they attend a police convention in New York, Chan picks up the case he was working on.
On a cruise ship from Honolulu to San Francisco, the famous Chinese detective encounters four more murders while trying to figure out the murder of a Scotland Yard friend.
In Rio de Janiero to arrest a nightclub singer on suspicion of a murder in Hawaii, Charlie Chan becomes involved with the Rio police in solving the singer's own murder.