Holly & Nathan Teller live in a small town in Pennsylvania. Holly is on the cheerleading team and has a close relationship with her younger brother Nathan, who is subjected to bullying at school. Nathan is taken for a car ride one day by the bullies, whose intent about what they are going to do with Nathan is not clear. He gives them the slip, but disappears and is still missing after three years.
A down to earth school psychologist tries to help a mentally ill student who actually believes his brother is coming back from the grave for revenge on the students who killed him.
Seven college students are picked to travel to a private island owned by the reclusive Vincent King and his film-obsessed wife Mary Shelley to study island wildlife. But is isn't long when a mysterious killer begins killing the students one-by-one, and modeling them after gory murder scenes from numerous horror films.
