Quirky and rebellious April Burns lives with her boyfriend in a low-rent New York City apartment miles away from her emotionally distant family. But when she discovers that her mother has a fatal form of breast cancer, she invites the clan to her place for Thanksgiving. While her father struggles to drive her family into the city, April -- an inexperienced cook -- runs into kitchen trouble and must ask a neighbor for help.
The Popes are a family who haven't been able to use their real identity for years. In the late sixties, the parents set a weapons lab afire in an effort to hinder the government's Vietnam war campaign. Ever since then, the Popes have been on the run with the authorities never far behind. Their survival is threatened when their eldest son falls in love with a girl, and announces his wish to live his life on his own terms.
A priest is put in a dilemma when the serial killer who has been murdering priests and nuns confesses to him.
