Due to a genetic disorder, handsome librarian Henry DeTamble involuntarily zips through time, appearing at various moments in the life of his true love, the beautiful artist Clare Abshire.
When disc jockey Grant Mazzy reports to his basement radio station in the Canadian town of Pontypool, he thinks it's just another day at work. But when he hears reports of a virus that turns people into zombies, Mazzy barricades himself in the radio booth and tries to figure out a way to warn his listeners about the virus and its unlikely mode of transmission.
Estranged from the rest of the townsfolk, an eccentric lady is haunted by ghostly whispers that grow louder with each passing day.
