Satoko is a high school student. She has a caring family and close friends. Her life seems comfortable, but she has an eating disorder. Satoko's anxiety gets worse as well. Because of this, Satoko's relationship with her family and friends becomes strained. One day, Satoko meets a woman, Maki, on the street and gets close to her.
Ai's mother sends her to live with a cult commune, where she remains for seven years. After the cult is broken up by the police, Ai struggles to fit in with society.
Dormant, experimental cells begin to awaken inside their human hosts, turning them into creatures called 'Amazons'. Two Amazons- Jin Takayama and Haruka Mizusawa- transform into Kamen Riders Amazon Alpha and Amazon Omega, aiming to exterminate the growing threat.
