Two friends in Mexico discover the Lament Configuration and unleash Pinhead, but one decides to try to survive by swapping himself with someone else. Once they go missing, family members go in search of them, but find Pinhead instead.
April works at a prestigious hospital in New York and has recently met a handsome veterinarian named Jesse. Jesse receives an invitation to his brother's wedding, so he and April travel to Amish Country to meet with those Jesse left behind years ago.
A former U.S. marshal discovers that all of the survivors of his old unit are experiencing the same symptoms simultaneously and there may be a larger conspiracy at hand.
