An obsessive, insubordinate homicide cop is convinced a serial killer is loose in the Hollywood area and disobeys orders in order to catch him.
Harry Mitchell is a successful Los Angeles manufacturer whose wife is running for city council. His life is turned upside down when three blackmailers confront him with a videotape of him with his young mistress and demand $100,000. Fearing that the story will hurt his wife's political campaign if he goes to the police, Harry pretends that he will pay the men, but does not follow through.
Amanda's deathbed request to her son, John, was for him to destroy all the lab notes etc. from her last experiment. She also blurts out he had a brother. At the funeral John meets Melissa, who claims to be his mother's biggest fan. Together with some of John's friends they go to Amanda's house, but none are prepared for what they find there.
