Yuki Cross, along with her best friend Zero, attempts to keep the peace between humans and vampires at Cross Academy, but personal issues soon threaten the situation.
Natsume Takashi has the ability to see spirits, which he has long kept secret. However, once he inherits a strange book that belonged to his deceased grandmother, Reiko, he discovers the reason why spirits surround him.
The 31st year of the Showa Era (1956) marked the tenth year since Japan's defeat in World War II. It was when Japan took its first step out of post-war poverty to rejoin the international community. In old downtown Tokyo, a teacher and her students try to pass down Doyo (Japanese traditional children's songs) as the root of Japanese cultural identity to the future generations.