After he inherits some money, Harold Bissonette ("pronounced bis-on-ay") decides to give up the grocery business, move to California and run an orange grove. Despite his family's objections and the news that the land he bought is worthless, Bissonette packs up and drives out to California with his nagging wife Amelia and children.
A mad scientist uses captured criminals as experiments for his study on "the criminal mind" aboard his private ship.
A wagon train heads west from Independence, Mo., along the Oregon Trail, led by proud cowboy Clint Belmet. On board are feisty young widow Nancy Wellington and her toddler, Sonny, as well as the older Abby Masters, who begins a romance with scout Jim Burch. Along the way, the wagon train battles Indians led by Kenneth Murdock, a trapper who doesn't welcome competition for Oregon's lucrative fur trade. Wagon Wheels is a 1934 remake of 1931's Fighting Caravans, using stock footage from the original.
