Robert Neville is a scientist who was unable to stop the spread of the terrible virus that was incurable and man-made. Immune, Neville is now the last human survivor in what is left of New York City and perhaps the world. For three years, Neville has faithfully sent out daily radio messages, desperate to find any other survivors who might be out there. But he is not alone.
After losing his job and wife, and spending time in an institution, a former teacher winds up living with his parents. He wants to rebuild his life and reconcile with his wife, but his father would be happy if he shared his obsession with the Philadelphia Eagles. Things get complicated when he meets Tiffany Maxwell who offers to help him reconnect with his wife if he will do something very important for her in exchange.
The life of an unsuccessful writer is transformed by a top-secret 'smart drug' that allows him to use 100% of his brain and become a perfect version of himself. His enhanced abilities soon attract shadowy forces that threaten his new life.
