After Homer accidentally pollutes the town's water supply, Springfield is encased in a gigantic dome by the EPA and the Simpsons are declared fugitives.
Ten years after she was separated from her family, an eighteen-year-old orphan with vague memories of the past sets out to Paris in hopes of reuniting with her grandmother. She is accompanied by two con men, who intend to pass her off as the Grand Duchess Anastasia to the Dowager Empress for a reward.
A young man finds out that he holds the key to restoring hope and ensuring survival for the human race, while an alien species called the Drej are bent on mankind's destruction.
