Three students get caught in the struggle between a good vampire and his evil brother in the Transylvanian mountains.
Continuing after the first "Subspecies", a woman who has just become a vampire tries to escape the evil vampire, Radu, who seeks her as his love interest. But she has taken the vampire family's bloodstone, and now Radu must find her to get it back. While her sister comes to Romania to save her soul. It might be too late....
Vampire fledgling Michelle Morgan has escaped the grasp of her master Radu Vladislas. Found by a woman named Ana, she is taken to a hospital where a doctor claims to be able to cure her vampirism. Radu, recovering from the near-death delivered by Michelle and her friends, travels to Bucharest to follow his fledgling. He visits the vampire Ash's stronghold. Ash and his protege Serena plot to destroy Radu and employ the help of the humans, Ana and the Doctor.
