Suffering from acute kidney failure, Boonmee has chosen to spend his final days surrounded by his loved ones in the countryside. Surprisingly, the ghost of his deceased wife appears to care for him, and his long lost son returns home in a non-human form. Contemplating the reasons for his illness, Boonmee treks through the jungle with his family to a mysterious hilltop cave—the birthplace of his first life.
At a Thai hospital, a doctor and his seven nubile nurses engage in the sale of dead bodies. Jealousy causes one of the nurses to threaten to blow the whistle on the practice, so the others murder her. Soon the spirit of the slain nurse seeks revenge. In flashbacks we see the events leading up to the murder, and realize the full range of relationships between the main characters.
Jeab, a young man working in Bangkok, receives word that his childhood sweetheart, Noi-Naa is to be married. While driving back to his hometown, the memories from his childhood come flooding back.
