Rebeca murders her sister Adriana to end up with the man she loved, and becomes the step mother of her niece Lucía. Nora, Lucía's half sister and daughter of Rebeca, resents Lucía for the same reasons Rebeca hated Adriana, as history repeats itself.
After running into something with her car, Vero experiences a particular psychological state. She realizes she might have killed someone.
The story of Secrets at the Hotel begins in 1908. Julio Olmedo and Isabel Alarcón travel on the same train to the Gran Hotel, property of the Alarcón family. Both of them ignore that their lives will take a new twist in that place, produced by love, treason, and the secrets hidden there.
