Raoul Duke and his attorney Dr. Gonzo drive a red convertible across the Mojave desert to Las Vegas with a suitcase full of drugs to cover a motorcycle race. As their consumption of drugs increases at an alarming rate, the stoned duo trash their hotel room and fear legal repercussions. Duke begins to drive back to L.A., but after an odd run-in with a cop, he returns to Sin City and continues his wild drug binge.
Two teenage couples traveling across the backwoods of Texas searching for urban legends of serial killers end up as prisoners of a bizarre and sadistic backwater family of serial killers.
A mild-mannered professor moonlighting as a fake hit man in police stings ignites a chain reaction of trouble when he falls for a potential client.
