The offspring of sportsman canine Air Bud: B-Dawg, Mudbud, Budderball, Buddha, and Rosebud, uncover a kidnapping plot motivated by a little rich boy's desire to have the world's most athletic dog as a pet.
Ray and Sal, two orphaned sisters, adopt and hide a Great Dane puppy from their two adopted parents living in a luxury downtown New York apartment that expressely forbids dogs.
Josh is off to his first year of college and Buddy has stayed behind with Josh’s little sister Andrea and the rest of the family. Andrea, attempting to fit in with her Jr. High classmates, decides to join the baseball team and along the way discovers that Buddy is a talented baseball player.
