4400 centers on the return of 4400 people who, previously presumed dead or reported missing, reappear on Earth. Though they have not aged physically, some of them seem to have deeper alterations ranging from superhuman strength to an unexplained healing touch. A government agency is formed to track the 4400 people after one of them commits a murder.
Steve Clark is a newcomer in the town of Cradle Bay, and he quickly realizes that there's something odd about his high school classmates. The clique known as the "Blue Ribbons" are the eerie embodiment of academic excellence and clean living. But, like the rest of the town, they're a little too perfect. When Steve's rebellious friend Gavin mysteriously joins their ranks, Steve searches for the truth with fellow misfit Rachel.
Marty Mackenzie is an unsuccessful stage actor who takes an interest in private investigating. He takes a job working with Jack Potter, a crusty private eye. They both take a case in Beaver Ridge, a seedy small town where a murder is being planned against a rich gravel pit owner. Marty realizes that private investigating is not as it seemed to be.
