Marcus Burnett is a henpecked family man. Mike Lowrey is a footloose and fancy free ladies' man. Both Miami policemen, they have 72 hours to reclaim a consignment of drugs stolen from under their station's nose. To complicate matters, in order to get the assistance of the sole witness to a murder, they have to pretend to be each other.
Refined actress Lauren Ames finally has a chance to study with the great theatre professor Stanislav Korzenowski. Sandy Brozinsky, a brash, loud actress, decides through happenstance to also study with Korzenowski. The two women end up dating the same man (who turns out to be a double agent) and follow him across the country to force him to choose between them.
In this variation on director Vadim's own, more acclaimed Et Dieu Créa La Femme (1956, the same title in French), the vamp Robin Shea marries charming carpenter Billy Moran, only to get out of prison, but soon decides to seduce James Tiernan, who runs for state governor.
