After solving their last mystery at Spooky Island, the Mystery Inc. gang is back in Coolsville, where they are being honored with their very own exhibit at the Coolsonian Criminology Museum. However, when a masked villain steals costumes of classic monsters on display and brings them to life, the gang must come out of retirement to solve the case.
Chris Nielsen dies to find himself in a heaven more amazing than he could have ever dreamed of. There is one thing missing: his wife. After he dies, his wife Annie killed herself and went to hell. Chris decides to risk eternity in Hades for the small chance that he will be able to bring her back to heaven.
Set during the last days of the Ottoman Empire, a love triangle develops between Mikael, a brilliant medical student, the beautiful and sophisticated artist Ana, and Chris, a renowned American journalist based in Paris.
